Intoxicación por cafeína en un recien nacido prematuro Caffeine citrate is used as first-line therapy in neonates to treat or prevent apnea of prematurity. This is not the most recent version of this Review. Please comment on the current version. view the current version 20 Jan Si su bebé no tenía apnea ni bradicardia en UCIN o si la frecuencia o puede recibir medicamentos (teofilina o cafeína) para disminuir los episodios. Los bebés recién nacidos prematuros corren el riesgo de hernias, que.

Author: Kazrazil Malasho
Country: Tunisia
Language: English (Spanish)
Genre: Music
Published (Last): 5 December 2017
Pages: 311
PDF File Size: 11.62 Mb
ePub File Size: 18.12 Mb
ISBN: 868-7-61149-779-3
Downloads: 32510
Price: Free* [*Free Regsitration Required]
Uploader: Gokasa

Experimental studies showed that recently born rats whose mothers had received caffeine during pregnancy had altered respiratory pattern. To determine the influence of presence of caffeine in umbilical cord blood on apnea occurrence.

None of them showed significance Table 3. Admin Administrateur Offline Joined: J Pediatr Rio J. Logistic regression analysis showed that none of those variables was associated with presence of caffeine in umbilical cord blood.

Effects of maternal cafiena and caffeine habits on infantile apnea: ABC of antenatal care. Schreiber-Deturmeny E, Bruguerolle B. En la apnea, la respiracion cesa temporalmente y luego regresa a la normalidad. The study excluded neonates whose mothers received opioids or drugs that led to respiratory center depression, neonates who remained in mechanical ventilation during the first 4 days of life, with cerebral congenital malformations, perinatal asphyxia Apgar score under 7 at the 5th minute of lifePIVH degrees 3 and 4, major cardiac malformations, exchange transfusion before the fourth day of life, neonates who presented one isolated apnea with no need for drug or ventilatory treatment, and those that received methylxantine prior to extubation.

Group characteristics were analyzed using chi-square test, Fisher’s exact test, except for the birth weight prematuri Student’s t test and Apgar score Mann-Whitney test. The cafeinw determination of theophylline, theobromine and caffeine in plasma by high performance liquid chromatography. Methylxanthine treatment for apnea in preterm infants.


Median caffeine concentration of the 87 patients prsmaturo detectable caffeine in umbilical blood was 2. Neonates were divided into detectable and undetectable caffeine in umbilical cord blood.

The study population was constituted by neonates with mean gestational age of Echocardiogram was performed in all preterm neonates with clinical suspicion of PDA. Sintomas de apnea del sueno en los bebes.

Before the collection and inclusion, a consent term was read to the parents or person in charge. Simultaneous determination of caffeine and its primary demethylated metabolites premauro human plasma by high-performance liquid chromatography.

Table 1 shows the group characteristics.

Un recien nacido prematuro es aquel que nace antes de completar la semana 37 de ges-tacion2, feina no solo mejora las apnea del pretermi- El diagnostico de apnea del prematuro debe plantearse despues de excluir infecciones, inestabilidad termica, hemorragia intracraneana http: Newborns were followed for the first 4 days for occurrence of apnea spells. Determination of caffeine, theophylline and theobromine in serum and saliva using high performance liquid chromatography.

Níveis plasmáticos de cafeína no cordão umbilical e apneia da prematuridade

La apnea del sueno en el bebe prematuro. Manuscript submitted Oct 20accepted for publication Jan 21 Discussion This study showed that neonates with detectable and undetectable levels of caffeine in umbilical cord blood had similar occurrence of apnea, and among the neonates who presented apnea, occurrence was later in preterm neonates with detectable levels of caffeine. Tratamientos para evitar la apnea. Definicion Apnea significa interrupcion prematuri la respiracion. Acknowledgements We thank Vania Naomi Hirakata for her assistance with the statistical analysis, and Carmen Pilla, BSc, for her assistance with the caffeine laboratory analysis.


Simultaneous high-performance liquid chromatographic determination of caffeine and theophylline for routine drug monitoring in human plasma. Como citar este artigo.

Apnea del prematuro (para Padres)

Preterm infants with birth weight of to 1, g treated with caffeine during the first 10 days have a reduced rate of bronchopulmonary dysplasia, and present fafeina better neurodevelopmental outcome at 18 to 21 months than a control group.

Blood samples were collected from umbilical blood using syringes with heparin. Apnea del Prematuro “Sugerimos que “apnea” se defina como un intervalo premauro respiracion que el recien nacido no pueda tolerar sin bradicardia o Algunos bebes que siguen teniendo apnea seran dados de alta del hospital con un monitor de apnea casero, con o sin cafeina, Bebe prematuro Siga leyendo. In the group with no detected caffeine in umbilical cord blood, gestational age was significantly lower, and they required more respiratory support, suggesting a role for immaturity in this group of patients.

This study aimed at determining the influence of presence pdematuro caffeine in umbilical cord blood on the incidence and time of occurrence of apnea of prematurity in the first days of life. Caffeine ne probably the most frequently drug taken in the world, consumed by people of all ages.

There was a problem providing the content you requested

Long-term effects of caffeine therapy for apnea of prematurity. N Engl J Med. Preterm neonates who fulfilled the inclusion criteria had their umbilical venous blood collected, immediately after birth.

No conflicts of interest declared concerning the publication of this article.